Batch processes are flexible allowing the production of different products within the same facility, and suitable for producing low volume, high value-added products such as pharmaceuticals and agrochemicals.The trend towards batch processing has necessitated the development of scheduling techniques.In addition to process scheduling, heat integrati
ABSTRACT The global rise of antibiotic resistance has renewed interest in phage therapy, as an alternative to antibiotics to eliminate multidrug-resistant (MDR) bacterial pathogens.However, optimizing the broad-spectrum efficacy of phage therapy remains a challenge.In this study, we addressed this issue by employing strategies to improve antimicrob
Casitas B-lineage lymphoma-b (Cbl-b) is a ubiquitin ligase (E3) that modulates signaling by tagging molecules for degradation.It is a complex protein with multiple domains and binding partners that are not involved in ubiquitinating substrates.Herein, we demonstrate that Cbl-b, but not c-Cbl, is recruited to the clustered B cell antigen Truck Model
Research Locomotive represents an essential component of the response to infectious disease outbreaks and to other public health emergencies, whether they are localised, of international concern, or global.Research conducted in such contexts also comes with particular ethics challenges, the awareness of which has significantly grown following the E